Home

Clinical Evidence

Only Alliforce™ delivers 100% readily absorbable Allicin, one of the most comprehensively studied biological substances. There are numerous clinical studies and trials on Allicin and below are excerpts of some of the many independent and published ones.

Excerpts of in vitro and in vivo clinical trials

“This study is the first to use a double-blind, placebo-controlled design to investigate the prevention of viral disease with a garlic supplement………..The results overwhelmingly favoured the supplement as a preventive measure, demonstrating accelerated relief, reduction in the severity of troublesome…”

“…volunteers in the active group were less likely to get a cold and recovered faster if infected. Volunteers taking placebo were much more likely to get more than one cold over the treatment period. An Allicin-containing supplement can prevent attack by the common cold virus.”

Josling, Peter. Preventing the Common Cold With a Garlic Supplement: A Double-Blind, Placebo-Controlled Survey Advances In Natural Therapy Volume 18 No. 4 July/August 2001.

“Allicin, one of the active principles of freshly crushed garlic homogenates, has a variety of antimicrobial activities….. found to exhibit

i)	antibacterial activity against a wide range of Gram-negative and Gram-positive bacteria, including multidrug-resistant enterotoxicogenic strains of Escherichia coli
ii)	antifungal activity, particularly against Candida albicans
iii)	antiparasitic activity, including some major ...”

Ankri, S., Mirelman, D. Antimicrobial properties of Allicin from garlic, Microbes and Infection, 2, 1999, 125-129.

“Some people living with HIV use garlic to enhance the immune system. Garlic may increase the number of natural killer cells, which destroy…”

Garlic. Community AIDS Treatment Information Exchange (CATIE) supplement sheet, Winter 2000.

“… diarrhea, genital herpes, candidiasis and pansinusitis with recurrent fever improved.”

Abdullah, T. H., et. al. Enhancement of Natural Killer Cell Activity in Aids with Garlic,
Deutsche Zeitschrift fur Onkologie 21, 1989.

“Allicin has the potential to assist the immune system in a number of different ways, stimulating immune cells, killing pathogens and detoxifying carcinogens.”

Cutler, Ronald R. The Immune System and Some Natural Agents That May Help It Fight Disease. The British Journal of Clinical Phytomedicine - Data review

“Allicin can inhibit telomerase activity and induce apoptosis of gastric cancer SGC-7901 cells. Allicin may be more effective than AZT.

Li Sun, Xu Wang. Effects of Allicin on both telomerase activity and apoptosis in gastric cancer SGC-7901 cel. World J Gastroenterol 2003 September;9(9):1930-1934

“Allicin based supplements do show an ability to prevent allergic reaction to pollen and may indeed offer a safe and natural alternative to pharmaceutical preparations.. clearly the treatment should be started as early as possible and continued throughout the season.…”

Steadman, S. and Josling, P. A pilot investigation into the use of Allimax for the treatment of Hay Fever (Seasonal Allergic Rhinitis). The British Journal of Clinical Phytomedicine, vol9, no 10.

“…Allicin is active in vitro against S. epidermidis and that sub-MICs of Allicin may play a role in the prevention of adherence of this bacteria to medical devices.”

Pe´rez-Giraldo, C., et. al. In vitro activity of Allicin against Staphylococcus epidermidis and influence of subinhibitory concentrations on biofilm formation. Journal of Applied Microbiology 2003, 95, 709–711.

“Experimentally, garlic and its associated sulfur components
are reported to suppress tumor incidence in breast, colon, skin,
uterine, esophagus and lung cancers”

Amagase, H. & Milner, J. A. (1993) Impact of various sources of garlic and their constituents on 7,12-dimethylbenz(a)anthracene binding to mammary cell DNA. Carcinogenesis 14: 1627–1631.

Ip, C., Lisk, D. J. & Stoewsand, G. S. (1992) Mammary cancer prevention by regular garlic and selenium-enriched garlic. Nutr. Cancer 7: 279–286.

Hussain, S. P., Jannu, L. N. & Rao, A. R. (1990) Chemopreventive action of garlic on methylcholanthrene-induced carcinogenesis in the uterine cervix of mice. Cancer Lett. 49: 175–180.

Liu, J. Z., Lin, R. I. & Milner, J. A. (1992) Inhibition of 7,12-dimethylbenz(a)- anthracene induced mammary tumors and DNA adducts by garlic powder. Carcinogenesis 13: 1847–1851.

Shukla, Y., Singh, A. & Srivastava, B. (1999) Inhibition of carcinogen-induced activity of gamma-glutamyl transpeptidase by certain dietary constituents in mouse skin. Biomed. Environ. Sci. 12: 110–115.

Song, K. & Milner, J. A. (1999) Heating garlic inhibits its ability to suppress 7, 12-dimethylbenz(a)anthracene-induced DNA adduct formation in rat mammary tissue. J. Nutr. 129: 657–661.

Sumiyoshi, H. & Wargovich, M. J. (1990) Chemoprevention of 1,2-dimethylhydrazine-
induced colon cancer in mice by natural occurring organosulfur compounds. Cancer Res. 50: 5084–5087.

Wargovich, M. J., Woods, C., Eng, V. W., Stephens, L. C. & Gray, K. (1988) Chemoprevention of N-nitrosomethylbenzylamine-induced esophageal cancer in rats by the naturally occurring thioether, diallyl sulfide. Cancer Res. 48: 6872–6875.